Biology 403, Evolution - Spring Semester, 2008 (sections 1 and 2)

Instructor (2nd half of the Spring semester): Matt Lavin, 308 & 339 Plant Bioscience Building, preferred manner of communication: email; otherwise: 994-2032.

Lecture section 01: 304 Lewis Hall on Monday, Wednesday, and Friday, 9:00-9:50 AM

Lecture section 02: 202 Reid Hall on Monday, Wednesday, and Friday, 1:10-2:00 PM

Office Hours. Mondays 10 AM – 12 N in 308 or 339 Plant Bioscience Building, or by appointment.

Text: Evolutionary Analysis, 4th ed., by Scott Freeman & Jon C. Herron (Prentice Hall). This text is on reserve at the front desk in the Renne Library.

Goals during the 2nd half of the course: The study of evolutionary history is the focus. In order to understand processes that occur over evolutionary time scales, the human mind needs to structure thought with theoretical concepts, including folk history, deterministic and stochastic processes, phylogeny, and monophyletic groups, for example. Evolutionary history relies on a genealogical theory that assumes all alleles, genes, individuals, populations, and higher taxa (species, genera, etc.) that have ever existed are related to various degrees by common descent. Because genes and genomes, not individuals, span evolutionary time scales, the study of the history of organisms is best done using genetic information. Methods such as Hardy-Weinberg equilibrium and phylogenetics enable biologist to study the process of speciation or diversification. These methods also have other applications such as in the study of wildlife biology, epidemiology, and human evolution. We will conclude this second section by addressing human nature and why it might be good to know something about it.

This course will not focus on theories that address the ultimate origins of life. If interested, a good starting point includes chapters 17 and 18 in Evolutionary Analysis, 4th edition. Most scientific activity in evolutionary history is centered on the mechanisms of change among the living species. Little of the fossil record will be covered, although contemporary methods of fossil analysis include the phylogenetic methods presented in this class.

PV92 data, mtDNA data (5’ variation, 3’ variation – African-Asian 5’ variation), mtDNA phylogeny

SCHEDULE OF LECTURES (please give me until the night before each lecture to finalize its content)

17 March – introduction

19 March – mutation & drift

21 March – University Day Holiday

24 March – population divergence

26 March – genetic drift

28 March – genetic drift continued

31 March – phylogenetics

2 April – phylogenetics continued

4 April – phylogenetics continued

7 April – phylogenetics continued

9 April – review

11 AprilExam #3

14 April – intro to cladistics

16 April – cladistic data sets

18 April – more cladistic data sets

21 April – cladistics reviewed

23 April – phylogenetic epidemiology

25 April – phylogenetic comparative method

28 April – speciation

30 April – human evolution

2 May – review

6 & 7 MayExam #4  (scores and final grades): 4:00-5:50 PM, 6 May (section 02) Reid 202, and 8:00-9:50 AM, 7 May (section 01) LH 304

GRADES will be derived from four exams. The dates of the last two exams in this final half of the course are given above. The four exams will each count one fourth of your grade. The test format and kinds of questions will be highly similar to the questions provided for each chapter in the text, Evolutionary Analysis, 4th edition. A list of specific text and web questions that relate to the material covered during each class will be posted with the lecture notes for that day.

Web sites with programs or servers that will or can be used during this course.

  • Dolan DNA Learning Center provides bioservers and information sources for the study of allelic variation and mtDNA sequences in human populations.
  • AlleleA1, Phylostrat, ForensicEA, and other software programs are available at a web site by Jon C. Herron, one of the authors of the textbook of this course.
  • ThetaSim, and other software programs are available at a web site by Paul O. Lewis at the University of Connecticut.
  • POPULUS. This program covers many topics in evolution and ecology.

The National Academy of Science has produced the following book on evolution: Science, Evolution, and Creationism.

Paleontologist Kevin Padian discusses the issues of gaps in the fossil record.

MSU Departments of Ecology, LRES (Kevin O'Neill – 1st half section 001) and Plant Sciences (Adam Richman – 1st half section 002,and Matt Lavin)